Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody

Details for Product No. ABIN196699
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Antigen
Synonyms STAT5A, STAT5, MGF, AA959963, Stat5, STAT5A/MGF, STATA5
Epitope
pSer780
(73), (37), (25), (20), (15), (10), (6), (4), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(296), (186), (166), (63), (61), (51), (36), (2), (1)
Host
Rabbit
(275), (41), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(9), (8), (7), (5), (5), (5), (5), (5), (5), (5), (5), (3), (2), (2), (1)
Application
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(250), (124), (111), (82), (50), (28), (27), (17), (16), (10), (8), (5), (2), (2), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 50 μg
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Catalog No. ABIN196699
286.00 $
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Immunogen The antiserum was produced against synthesized phosphopeptide derived from human STAT5A around the phosphorylation site of serine 780 (R-L-SP-P-P).
Specificity The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site. STAT5A (phospho-Ser780) antibody detects endogenous levels of STAT5A only when phosphorylated at serine 780.
Purification Immunoaffinity chromatography.
Alternative Name STAT5 / STAT5A
Background Alternate names: MGF, Mammary gland factor, STAT-5, STAT-5A, Signal transducer and activator of transcription 5A
Gene ID 6776
NCBI Accession NP_003143
UniProt P42229
Application Notes Suitable for use in Western blot (1: 500~1: 1000) and Immunohistochemistry (1: 50~1: 100). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% Sodium Azide and 50% glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C.
Expiry Date 12 months
Supplier Images
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody
anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody (2) anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (pSer780) antibody (Image 2)
Background publications Gouilleux, Wakao, Mundt et al.: "Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription." in: The EMBO journal, Vol. 13, Issue 18, pp. 4361-9, 1994 (PubMed).

Meinke, Barahmand-Pour, Wöhrl et al.: "Activation of different Stat5 isoforms contributes to cell-type-restricted signaling in response to interferons." in: Molecular and cellular biology, Vol. 16, Issue 12, pp. 6937-44, 1997 (PubMed).

Dentelli, Del Sorbo, Rosso et al.: "Human IL-3 stimulates endothelial cell motility and promotes in vivo new vessel formation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 4, pp. 2151-9, 1999 (PubMed).

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