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CDK2 antibody (Thr160)
CDK2
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDK2 Antibody
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Target
See all CDK2 Antibodies
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Binding Specificity
All epitopes for CDK2 antibodies
Thr160
Reactivity
All reactivities for CDK2 antibodies
Human, Mouse, Rat
Host
All hosts for CDK2 antibodies
Rabbit
Clonality
All clonalities for CDK2 antibodies
Polyclonal
Conjugate
All conjugates for CDK2 antibodies
This CDK2 antibody is un-conjugated
Application
All applications for CDK2 antibodies
Western Blotting (WB)
Sequence
T-Y-TP-H-E
Specificity
This antibody detects endogenous levels of total CDK2 protein.
Purification
Affinity-chromatography using epitope-specific immunogen
Immunogen
Synthesized non-phosphopeptide derived from human CDK2 around the phosphorylation site of threonine160.
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Discover our top product CDK2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western blot (1: 500 - 1: 1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store (in aliquots) at -20 °C.
Target Details for CDK2
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Target
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Alternative Name
CDK2 (CDK2 Products )
Synonyms
p33(CDK2) antibody, A630093N05Rik antibody, wu:fa10c02 antibody, zgc:56598 antibody, zgc:77684 antibody, eg1 antibody, CDKN2 antibody, cdk2L antibody, cyclin dependent kinase 2 antibody, cyclin-dependent kinase 2 antibody, cyclin-dependent kinase 2 S homeolog antibody, CDK2 antibody, Cdk2 antibody, cdk2 antibody, cdk2.S antibody
Background
Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase
Gene ID
1017
NCBI Accession
NP_001789
UniProt
P24941
Pathways
PI3K-Akt Signaling , Cell Division Cycle , Mitotic G1-G1/S Phases , DNA Replication , M Phase , Synthesis of DNA
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