Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Tyr14) antibody

Details for Product No. ABIN197288
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Antigen
Synonyms fc07c04, wu:fc07c04, Cav-1, bscl3, cav1, cav1a, cgl3, vip21, cav1b, caveolin-1, cav, mstp085, Caveolin-1, CAV1, cav-1, Cav, caveolin 1, BSCL3, CGL3, MSTP085, PPH3, VIP21
Epitope
Tyr14
(35), (33), (23), (6), (6), (5), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(193), (120), (118), (22), (20), (15), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(168), (28), (13), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(149), (55), (46), (44), (30), (27), (26), (20), (4), (1), (1), (1)
Pubmed 5 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN197288
308.00 $
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Immunogen Synthesized non-phosphopeptide derived from human Caveolin-1 around the phosphorylation site of tyrosine 14
Sequence H-L-YP-T-V
Specificity This antibody detects endogenous levels of total Caveolin-1 protein.
Purification Affinity-chromatography using epitope-specific immunogen
Alternative Name Caveolin-1
Background Alternate names: CAV1
Gene ID 857
NCBI Accession NP_001744
UniProt Q03135
Research Area Signaling
Application Notes Western blot: (1: 500 - 1: 1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Expiry Date 12 months
Supplier Images
anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Tyr14) antibody anti-Caveolin 1, Caveolae Protein, 22kDa (CAV1) (Tyr14) antibody
Background publications Maggi, Biedi, Segat et al.: "IGF-I induces caveolin 1 tyrosine phosphorylation and translocation in the lipid rafts." in: Biochemical and biophysical research communications, Vol. 295, Issue 5, pp. 1085-9, 2002 (PubMed).

Labrecque, Royal, Surprenant et al.: "Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol." in: Molecular biology of the cell, Vol. 14, Issue 1, pp. 334-47, 2003 (PubMed).

Fielding, Chau, Liu et al.: "Mechanism of platelet-derived growth factor-dependent caveolin-1 phosphorylation: relationship to sterol binding and the role of serine-80." in: Biochemistry, Vol. 43, Issue 9, pp. 2578-86, 2004 (PubMed).

Labrecque, Nyalendo, Langlois et al.: "Src-mediated tyrosine phosphorylation of caveolin-1 induces its association with membrane type 1 matrix metalloproteinase." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52132-40, 2004 (PubMed).

Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

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