TNFRSF10B antibody

Catalog No. ABIN199108

This Rabbit Polyclonal antibody specifically detects TNFRSF10B in WB and FACS. It exhibits reactivity toward Human.

Quick Overview for TNFRSF10B antibody (ABIN199108)

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNFRSF10B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-TNFRSF10B Antibody

Specificity: Recognizes human DR5.

Purification: Affinity purified

Immunogen: Recombinant DR5.

Type of Immunogen: Recombinant protein

Application Details

Application Notes: Approved: Flo, WB (1 - 2 μg/mL)

Usage: Flow cytometry. Western Blot. Induction of apoptosis. Western Blot: 1-2 μg/mL. Flow Cytometry: 3 μg/1 x10⁶. Induction of Apoptosis: 2.5 μg/mL for 12 hours (10-12 % in Jurkat cells).

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 100 mM borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added.

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for TNFRSF10B

Target: TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))

Alternative Name: TNFRSF10B / Killer / DR5

Background: Name/Gene ID: TNFRSF10B
Family: TNF Receptor

Synonyms: TNFRSF10B, Cytotoxic TRAIL receptor-2, CD262 antigen, DR5, Death receptor 5, KILLER, TRAIL-R2, TRICK2B, TRAILR2, TRICK2A, TRICKB, TRICK2, CD262, Fas-like protein, TRAIL receptor 2, ZTNFR9

Gene ID: 8795

UniProt: O14763

Pathways: p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity