MMP14 antibody (AA 112-582) (HRP)

Catalog No. ABIN1993093

Product Details anti-MMP14 Antibody (HRP)

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Binding Specificity: AA 112-582

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP14 antibody is conjugated to HRP

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Matrix metalloproteinase-14 protein (112-582AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin^TM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze.
Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MMP14

Target: MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

Alternative Name: MMP14 (MMP14 Products)

Synonyms: MMP1 antibody, MMP-14 antibody, MMP-X1 antibody, MT-MMP antibody, MT-MMP 1 antibody, MT1-MMP antibody, MT1MMP antibody, MTMMP1 antibody, mmp-x1 antibody, mt1-mmp antibody, mtmmp1 antibody, AI325305 antibody, MT-MMP-1 antibody, sabe antibody, Mt1-mmp antibody, MT-MMPbeta antibody, cb386 antibody, sb:cb386 antibody, wu:fb72b09 antibody, mmp14 antibody, matrix metallopeptidase 14 antibody, matrix metallopeptidase 14 (membrane-inserted) antibody, matrix metallopeptidase 14b (membrane-inserted) antibody, matrix metallopeptidase 14a (membrane-inserted) antibody, matrix metallopeptidase 14 L homeolog antibody, MMP14 antibody, mmp14 antibody, Mmp14 antibody, mmp14b antibody, mmp14a antibody, mmp14.L antibody

Background:

Background: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.

Aliases: Matrix metallopeptidase 14 (membrane inserted) antibody, Matrix metalloproteinase 14 antibody, Matrix metalloproteinase-14 antibody, Membrane type 1 matrix metalloproteinase antibody, Membrane type 1 metalloprotease antibody, Membrane type matrix metalloproteinase 1 antibody, Membrane-type matrix metalloproteinase 1 antibody, Membrane-type-1 matrix metalloproteinase antibody, MMP 14 antibody, MMP X1 antibody, MMP-14 antibody, MMP-X1 antibody, Mmp14 antibody, MMP14_HUMAN antibody, MMPX1 antibody, MT MMP 1 antibody, MT-MMP 1 antibody, MT1 MMP antibody, MT1-MMP antibody, MT1MMP antibody, MTMMP 1 antibody, MTMMP1 antibody

UniProt: P50281

Pathways: Autophagy