EMR3 antibody (FITC)

Catalog No. ABIN207230

Product Details anti-EMR3 Antibody (FITC)

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Reactivity: Human

Host: Hamster

Clonality: Monoclonal

Conjugate: This EMR3 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: Recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), which is a 56kD member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. The molecule is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, hematopoietic stem cells and myeloid progenitors. Studies suggest that the EMR3 Molecule is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells. The exact functions of EMR3 and its ligands have not yet been determined.

Purification: Protein G purified

Immunogen: ARHO-EMR3-CD97 (EGF1) transfectants.

Isotype: IgG

Application Details

Application Notes: Approved: Flo (1:1 - 1:10), IP

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for EMR3

Target: EMR3 (Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 3 (EMR3))

Alternative Name: ADGRE3 / EMR3 (EMR3 Products)

Synonyms: EMR3 antibody, DKFZp459A1439 antibody, adhesion G protein-coupled receptor E3 antibody, ADGRE3 antibody, EMR3 antibody

Background: Name/Gene ID: ADGRE3
Subfamily: Orphan-B
Family: GPCR

Synonyms: ADGRE3, EGF-like module receptor 3, EMR3

Gene ID: 84658

UniProt: Q9BY15