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Integrin beta 2 antibody (Activation Site)

ITGB2 Reactivity: Human FACS, WB, IP Host: Mouse Monoclonal unconjugated

Catalog No. ABIN211663

Datasheet as PDF

Target See all Integrin beta 2 (ITGB2) Antibodies

Integrin beta 2 (ITGB2)
Binding Specificity
19

15

8

7

6

6

5

4

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Activation Site
Reactivity
191

53

43

9

6

3

3

2

2

2

2

2

2

2

1

1
Human
Host
99

87

35

2

1

1
Mouse
Compatible Secondaries
Clonality
131

89

2
Monoclonal
Conjugate
100

22

20

16

8

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This Integrin beta 2 antibody is un-conjugated
Application
129

81

51

44

37

32

28

26

26

25

22

12

8

3

3

3

2

2

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Specificity

Recognizes an epitope on the human CD18 Molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by MEM-148 is also exposed during dissociation of the CD11/CD18 by low  pH .

Purification

Protein G purified

Immunogen

Peripheral blood mononuclear cells. ( ACTIVATION EPITOPE ).

Isotype

IgG1

Top Product

Discover our top product ITGB2 Primary Antibody
anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reactivity: Human FACS, WB, IP, IHC (fro), IHC (p) Host: Mouse Monoclonal MEM-48 unconjugated

anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reactivity: Human FACS, WB, IP, IHC (fro), Func, IHC (p) Host: Mouse Monoclonal MEM-48 unconjugated

anti-Integrin beta 2 (ITGB2) antibody (FITC)
ITGB2 Reactivity: Human FACS Host: Mouse Monoclonal MEM-48 FITC

anti-Integrin beta 2 (ITGB2) antibody (Biotin)
ITGB2 Reactivity: Human FACS, WB, IP, IHC (fro), IHC (p) Host: Mouse Monoclonal MEM-48 Biotin

anti-Integrin beta 2 (ITGB2) antibody (PE)
ITGB2 Reactivity: Human FACS Host: Mouse Monoclonal MEM-48 PE

anti-Integrin beta 2 (ITGB2) (AA 70-170) antibody
ITGB2 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reactivity: Mouse FACS, WB, IP, IHC (fro), Func, IHC (p) Host: Rat Monoclonal M18-2 unconjugated

anti-Integrin beta 2 (ITGB2) (AA 559-700) antibody
ITGB2 Reactivity: Human FACS, WB, ELISA Host: Mouse Monoclonal 3C11G5 unconjugated

anti-Integrin beta 2 (ITGB2) (AA 17-382) antibody
ITGB2 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 2 (ITGB2) antibody
ITGB2 Reactivity: Mouse FACS, WB, IP, IHC (fro), IHC (p) Host: Rat Monoclonal M18-2 unconjugated

Application Notes

Approved: Flo, IP, WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Reconstitution

deionized water

Concentration

Lot specific

Buffer

0.09 % sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeat freeze-thaw cycles.

Storage

4 °C,-20 °C

Storage Comment

Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Target

Integrin beta 2 (ITGB2)

Alternative Name

ITGB2 / MAC-1 / CD18 (ITGB2 Products)

Background

Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gene ID

3689

UniProt

P05107

Pathways

NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation