PTK2B antibody (pTyr402)

Catalog No. ABIN6735486

Product Details anti-PTK2B Antibody

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Binding Specificity: pTyr402

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PTK2B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Recognizes human Pyk2 phosphorylated at Tyr402. Species cross-reactivity: Mouse, Rat. Does not cross-react with the non-phosphorylated form of Pyk2/CAKb or with unrelated phosphorylation sites.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Gel Filtration Chromatography

Immunogen: Synthetic peptide corresponding to a portion of human Pyk2 (proline-rich tyrosine kinase 2) phosphorylated at Tyr402. Conjugated to KLH.

Isotype: IgG1

Application Details

Application Notes: ELISA (0.05 µg/mL), WB (0.5 µg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, 0.09% sodium azide, G, sucrose, 40% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for PTK2B

Target: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Alternative Name: PTK2B / PYK2 (PTK2B Products)

Synonyms: CADTK antibody, CAKB antibody, FADK2 antibody, FAK2 antibody, PKB antibody, PTK antibody, PYK2 antibody, RAFTK antibody, CAKbeta antibody, E430023O05Rik antibody, Raftk antibody, Pyk2 antibody, fak1b antibody, ptk2.2 antibody, ptk2b antibody, si:ch1073-355e8.1 antibody, protein tyrosine kinase 2 beta antibody, PTK2 protein tyrosine kinase 2 beta antibody, protein tyrosine kinase 2aa antibody, PTK2B antibody, Ptk2b antibody, ptk2aa antibody

Background: Standard Gene Symbol: PTK2B, Gene Family: Protein Kinase, Gene Subfamily: Focal Adhesion Kinase, Synonyms: PTK2B, CADTK, CAKB, Cell adhesion kinase beta, FADK 2, FADK2, Focal adhesion kinase 2, FRNK, FAK2, Proline-rich tyrosine kinase 2, Protein-tyrosine kinase 2-beta, Protein kinase B, Protein tyrosine kinase 2 beta, PYK2, RAFTK, CAK-beta, PKB, PTK

Molecular Weight: 116kDa

Gene ID: 2185

UniProt: Q14289

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling