CD40 Ligand antibody
-
- Target See all CD40 Ligand (CD40LG) Antibodies
- CD40 Ligand (CD40LG)
-
Reactivity
- Mouse
-
Host
-
Hamster
-
Clonality
- Monoclonal
-
Conjugate
- This CD40 Ligand antibody is un-conjugated
-
Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
- Specificity
- Recognizes CD154 (mouse CD40 ligand/gp39), Mr 39kD. Binds to murine CD154 with high affinity, blocks binding to CD40, and blocks CD154 function. Administration of this antibody to mice blocks the ability to mount primary and secondary immune responses to TD antigens, yet does not alter the immune response to TI antigens.
- Purification
- Purified
- Immunogen
-
Activated mouse Th1 clone D1.6.
Type of Immunogen: Cells - Clone
- MR1
- Isotype
- IgG kappa
- Top Product
- Discover our top product CD40LG Primary Antibody
-
-
- Application Notes
-
Approved: Flo, Func, IP
Usage: Suitable for use in Flow Cytometry, Immunoprecipitation and in vivo and in vitro blockage of CD154 function. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. - Comment
-
Target Species of Antibody: Mouse
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS. No preservative added.
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
-
Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.
-
- Target
- CD40 Ligand (CD40LG)
- Alternative Name
- CD40LG / CD40L / CD154 (CD40LG Products)
- Synonyms
- CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody
- Background
-
Name/Gene ID: CD40LG
Family: TNF
Synonyms: CD40LG, CD154, CD154 antigen, CD40-L, CD40 ligand, CD40L, gp39, HIGM1, IGM, IMD3, T-BAM, TNFSF5, CD40 antigen ligand, CD54, HCD40L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein - Gene ID
- 959
- UniProt
- P29965
- Pathways
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
-