Specific to the proMBP subunit of heterotetrameric PAPP-A (htPAPP-A, PAPP-A/proMBP). Human PAPP-A antigen purified from placental blood is a heterotetrameric complex, consisting of two PAPP-A subunits and two pro-MBP subunits). Human PAPP-A antigen purified from atherosclerotic plaques is homodimeric consisting of 2 PAPP-A subunits.
Characteristics
MAb to PAPP-A (proMBP), Monoclonal antibody to Human Pregnancy Associated Plasma Protein A (PAPP-A)
Purification
Protein A Chromatography. Ascites
Immunogen
Purified human PAPP-A/proMBP heterotetrameric complex (htPAPP-A)
PAPPA
Reactivity: Human
WB, IHC, ICC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Detection of human htPAPP-A antigen in immunoassay and immunoprecipitation. Recognizes proMBP subunit in Western blot. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.1 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store at 2-8 °C.
Target
PAPPA
(Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
Alternative Name
Pregnancy Associated Plasma Protein A (PAPP-A) (PAPPA Products)