GDF15 antibody (N-Term)
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- Target See all GDF15 Antibodies
- GDF15 (Growth Differentiation Factor 15 (GDF15))
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Binding Specificity
- AA 30-194, N-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This GDF15 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Cell-ELISA (cELISA)
- Purification
- Protein G
- Immunogen
- genetic immunisation with cDNA encoding aa30-194 (N-term) of MIC-1 proprotein
- Clone
- ME-6D10
- Isotype
- IgG1
- Top Product
- Discover our top product GDF15 Primary Antibody
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anti-Growth Differentiation Factor 15 (GDF15) (AA 49-308) antibody
GDF15 Reactivity: Human WB, IHC, IP, IF Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibodyVerified GDF15 Reactivity: Human WB, ELISA, IHC, FACS Host: Goat Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (Biotin)GDF15 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal Biotin
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79) antibodyGDF15 Reactivity: Human WB, ELISA, IHC, FACS Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 30-308) antibodyGDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 221-308) antibodyGDF15 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 51-79), (N-Term) antibodyGDF15 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB30209 unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (C-Term) antibody (HRP)GDF15 Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal HRP
anti-Growth Differentiation Factor 15 (GDF15) (AA 195-308) antibodyGDF15 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Growth Differentiation Factor 15 (GDF15) (AA 198-308) antibodyGDF15 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. - Comment
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Synonyms: GDF15
- Restrictions
- For Research Use only
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- Buffer
- PBS, pH 7.2
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C
- Storage Comment
- short term: 2 °C - 8 °C, long term: -20 °C
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- Target
- GDF15 (Growth Differentiation Factor 15 (GDF15))
- Alternative Name
- MIC-1 (GDF15 Products)
- Synonyms
- GDF15 antibody, GDF-15 antibody, MIC-1 antibody, MIC1 antibody, NAG-1 antibody, PDF antibody, PLAB antibody, PTGFB antibody, SBF antibody, growth differentiation factor 15 antibody, GDF15 antibody, Gdf15 antibody
- Background
- Macrophage inhibitory cytokine-1 (MIC-1) is a member of the transforming growth factor-ß superfamily that regulates a wide variety of physiological processes involved in tissue differentiation and maintenance. MIC-1 is synthesized as a 62-kDa intracellular protein, which, after cleavage by a furin like protease, is secreted as a 25-kDa disulphide-linked dimeric protein. Expression of MIC-1 results in inhibition of macrophage activation, regulated by the p53 pathway, in response to pro-inflammatory monokines. MIC-1 is involved in tumour pathogenesis and its measurement can be used as a clinical tool for the diagnosis of a wide range of cancers. It could be a useful marker for aggressive prostate cancer while MIC-1 is upregulated in advanced and more aggressive prostatic tumours.
- UniProt
- Q99988
- Pathways
- SARS-CoV-2 Protein Interactome
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