PFKP antibody

Catalog No. ABIN2429444

Product Details anti-PFKP Antibody

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKP antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purification: Affinity purification

Immunogen: Recombinant protein of human PFKP

Isotype: IgG

Application Details

Application Notes: IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Handling Advice: Avoid freeze / thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PFKP

Target: PFKP (phosphofructokinase, Platelet (PFKP))

Alternative Name: PFKP (PFKP Products)

Synonyms: pfk antibody, pfk-c antibody, pfkf antibody, PFKP antibody, PFK-C antibody, PFKF antibody, 1200015H23Rik antibody, 9330125N24Rik antibody, PFKM antibody, phosphofructokinase, platelet antibody, phosphofructokinase, platelet S homeolog antibody, ATP-dependent 6-phosphofructokinase, platelet type antibody, pfkp antibody, PFKP antibody, pfkp.S antibody, LOC100549777 antibody, Pfkp antibody

Background: The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM, MIM 610681) and liver (PFKL, MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Pathways: Warburg Effect