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CD137 antibody
TNFRSF9
Reactivity: Human
ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CD137 Antibody
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Target
See all CD137 (TNFRSF9) Antibodies
CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Reactivity
All reactivities for CD137 antibodies
Human
Host
All hosts for CD137 antibodies
Rabbit
Clonality
All clonalities for CD137 antibodies
Polyclonal
Conjugate
All conjugates for CD137 antibodies
This CD137 antibody is un-conjugated
Application
All applications for CD137 antibodies
ELISA, Immunohistochemistry (IHC)
Purification
Affinity purification
Immunogen
Recombinant protein of human TNFRSF9
Isotype
IgG
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Discover our top product TNFRSF9 Primary Antibody
Alternatives
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Application Details
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Application Notes
IHC 1:25-1:100
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Handling Advice
Avoid freeze / thaw cycles.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CD137
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Target
CD137 (TNFRSF9)
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Alternative Name
CD137 (TNFRSF9 Products )
Synonyms
TNFRSF9 antibody, zgc:136557 antibody, 4-1BB antibody, CD137 antibody, CDw137 antibody, ILA antibody, A930040I11Rik antibody, AA408498 antibody, AI325004 antibody, Cd137 antibody, Ly63 antibody, tumor necrosis factor receptor superfamily member 9 antibody, TNF receptor superfamily member 9 antibody, tumor necrosis factor receptor superfamily, member 9a antibody, tumor necrosis factor receptor superfamily, member 9 antibody, TNFRSF9 antibody, tnfrsf9a antibody, Tnfrsf9 antibody
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB.
Pathways
Cancer Immune Checkpoints
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