SCMH1 antibody

Catalog No. ABIN2457910

Product Details anti-SCMH1 Antibody

Target: SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCMH1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCMH1.

Application Details

Application Notes: SCMH1 antibody can be used for detection of SCMH1 by ELISA at 1:62500. SCMH1 antibody can be used for detection of SCMH1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SCMH1 antibody at -20 °C.

Target Details for SCMH1

Target: SCMH1 (Sex Comb On Midleg Homolog 1 (SCMH1))

Alternative Name: SCMH1 (SCMH1 Products)

Synonyms: Scml3 antibody, AI315320 antibody, AI851618 antibody, Scml1 antibody, zgc:162582 antibody, Scm polycomb group protein homolog 1 antibody, sex comb on midleg homolog 1 (Drosophila) antibody, sex comb on midleg homolog 1 antibody, Scm polycomb group protein homolog 1 L homeolog antibody, SCMH1 antibody, Scmh1 antibody, scmh1 antibody, scmh1.L antibody

Background: SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Molecular Weight: 65 kDa

Gene ID: 22955

NCBI Accession: NP_036368