DGCR2 antibody

Catalog No. ABIN2459031

Product Details anti-DGCR2 Antibody

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DGCR2.

Application Details

Application Notes: DGCR2 antibody can be used for detection of DGCR2 by ELISA at 1:62500. DGCR2 antibody can be used for detection of DGCR2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DGCR2 antibody at -20 °C.

Target Details for DGCR2

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Alternative Name: DGCR2 (DGS2 Products)

Synonyms: DGS-C antibody, IDD antibody, LAN antibody, SEZ-12 antibody, CIDD antibody, 9930034O06Rik antibody, Dgsc antibody, Idd antibody, Lan antibody, Sez12 antibody, mKIAA0163 antibody, zgc:91974 antibody, DiGeorge syndrome critical region gene 2 antibody, DiGeorge syndrome critical region gene 2 S homeolog antibody, DGCR2 antibody, Dgcr2 antibody, dgcr2 antibody, dgcr2.S antibody

Background: Deletions of the 22q11.2 have been associated with a wide range of developmental defects classified under the acronym CATCH 22. The DGCR2 is a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.

Molecular Weight: 61 kDa

Gene ID: 9993

NCBI Accession: NP_005128

UniProt: P98153