DGCR2 antibody

Catalog No. ABIN7466608

Product Details anti-DGCR2 Antibody

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DGCR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human DGCR2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Comment:

Positive Control: MCF-7

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.48 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for DGCR2

Target: DGCR2 (DGS2) (DiGeorge Syndrome Chromosome Region-2 (DGS2))

Alternative Name: DiGeorge syndrome critical region gene 2 (DGS2 Products)

Synonyms: DGS-C antibody, IDD antibody, LAN antibody, SEZ-12 antibody, CIDD antibody, 9930034O06Rik antibody, Dgsc antibody, Idd antibody, Lan antibody, Sez12 antibody, mKIAA0163 antibody, zgc:91974 antibody, DiGeorge syndrome critical region gene 2 antibody, DiGeorge syndrome critical region gene 2 S homeolog antibody, DGCR2 antibody, Dgcr2 antibody, dgcr2 antibody, dgcr2.S antibody

Background: DiGeorge syndrome critical region gene 2 , DGS-C , IDD , LAN , SEZ-12,Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome. [provided by RefSeq]

Molecular Weight: 61 kDa

Gene ID: 9993

UniProt: P98153