Fibromodulin antibody

Catalog No. ABIN2459784

Product Details anti-Fibromodulin Antibody

Target: Fibromodulin (FMOD)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FMOD.

Application Details

Application Notes: FMOD antibody can be used for detection of FMOD by ELISA at 1:62500. FMOD antibody can be used for detection of FMOD by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store FMOD antibody at -20 °C.

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: FMOD (FMOD Products)

Synonyms: FMOD antibody, AI131919 antibody, AU041740 antibody, SLRR2E antibody, LOC100286414 antibody, sc:d0415 antibody, si:dkey-31j12.4 antibody, LOC100229381 antibody, FM antibody, fibromodulin antibody, fibromodulin b antibody, FMOD antibody, Fmod antibody, LOC100286414 antibody, fmodb antibody

Background: Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Molecular Weight: 41 kDa

Gene ID: 2331

NCBI Accession: NP_002014

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process