Fibromodulin antibody

Catalog No. ABIN7262178

Product Details anti-Fibromodulin Antibody

Target: Fibromodulin (FMOD)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Fibromodulin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human FMOD (NP_002014.2).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Fibromodulin

Target: Fibromodulin (FMOD)

Alternative Name: FMOD (FMOD Products)

Synonyms: FMOD antibody, AI131919 antibody, AU041740 antibody, SLRR2E antibody, LOC100286414 antibody, sc:d0415 antibody, si:dkey-31j12.4 antibody, LOC100229381 antibody, FM antibody, fibromodulin antibody, fibromodulin b antibody, FMOD antibody, Fmod antibody, LOC100286414 antibody, fmodb antibody

Background: Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 45 kDa

Calculated_MW: 43 kDa

Gene ID: 2331

UniProt: Q06828

Pathways: Glycosaminoglycan Metabolic Process