TUB antibody

Catalog No. ABIN2459995

Product Details anti-TUB Antibody

Target: TUB (Tubby Homolog (TUB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TUB.

Application Details

Application Notes: TUB antibody can be used for detection of TUB by ELISA at 1:1562500. TUB antibody can be used for detection of TUB by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TUB antibody at -20 °C.

Target Details for TUB

Target: TUB (Tubby Homolog (TUB))

Alternative Name: TUB (TUB Products)

Synonyms: rd5 antibody, tubby antibody, MGC79522 antibody, TUB antibody, MGC80126 antibody, MGC84061 antibody, tub antibody, tubby bipartite transcription factor antibody, tubby bipartite transcription factor S homeolog antibody, tub antibody, TUB antibody, tub.S antibody, Tub antibody

Background: TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight.This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

Molecular Weight: 62 kDa

Gene ID: 7275

NCBI Accession: NP_003311

UniProt: P50607

Pathways: RTK Signaling, Sensory Perception of Sound