H2AFY antibody
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- Target See all H2AFY Antibodies
- H2AFY (H2A Histone Family, Member Y (H2AFY))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFY antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by peptide affinity chromatography method.
- Immunogen
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human H2AFY.
- Top Product
- Discover our top product H2AFY Primary Antibody
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- Application Notes
- H2AFY antibody can be used for detection of H2AFY by ELISA at 1:12500. H2AFY antibody can be used for detection of H2AFY by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Handling Advice
- As with any antibody avoid repeat freeze-thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store H2AFY antibody at -20 °C.
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- Target
- H2AFY (H2A Histone Family, Member Y (H2AFY))
- Alternative Name
- H2AFY (H2AFY Products)
- Synonyms
- H2A.y antibody, H2A/y antibody, H2AF12M antibody, H2AFJ antibody, MACROH2A1.1 antibody, mH2A1 antibody, macroH2A1.2 antibody, mH2a1 antibody, macroH2A1 antibody, wu:fa93c12 antibody, zgc:136891 antibody, h2a.y antibody, h2a/y antibody, h2af12m antibody, h2afj antibody, macroh2a antibody, mh2a1 antibody, core histone macro-H2A.1 antibody, H2A histone family, member Y antibody, H2A histone family member Y antibody, H2A histone family member Y L homeolog antibody, LOC100230612 antibody, H2AFY antibody, LOC481514 antibody, H2afy antibody, h2afy antibody, h2afy.L antibody
- Background
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 39 kDa
- Gene ID
- 9555
- NCBI Accession
- NP_001035248
- UniProt
- O75367
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