WARS antibody

Catalog No. ABIN2460069

Product Details anti-WARS Antibody

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WARS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human WARS.

Application Details

Application Notes: WARS antibody can be used for detection of WARS by ELISA at 1:62500. WARS antibody can be used for detection of WARS by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store WARS antibody at -20 °C.

Target Details for WARS

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Alternative Name: WARS (WARS Products)

Synonyms: GAMMA-2 antibody, IFI53 antibody, IFP53 antibody, zgc:73274 antibody, wars antibody, MGC53671 antibody, WARS antibody, TrpRS antibody, WRS antibody, 85D-WRS antibody, CG9735 antibody, Dmel\\CG9735 antibody, WRS-85D antibody, l(3)03559 antibody, l(3)03560 antibody, l(3)3559 antibody, gamma-2 antibody, ifi53 antibody, ifp53 antibody, GB14934 antibody, ECK3371 antibody, JW3347 antibody, tryptophanyl-tRNA synthetase antibody, tryptophanyl-tRNA synthetase S homeolog antibody, Tryptophanyl-tRNA synthetase antibody, tryptophanyl-tRNA synthetase L homeolog antibody, tryptophan--tRNA ligase, cytoplasmic antibody, WARS antibody, wars antibody, wars.S antibody, Wars antibody, TrpRS antibody, wars.L antibody, LOC727582 antibody, trpS antibody, trpS2 antibody

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA (trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 52 kDa

Gene ID: 7453

NCBI Accession: NP_004175

UniProt: P23381