TAF11 antibody

Catalog No. ABIN2460381

Product Details anti-TAF11 Antibody

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TAF11.

Application Details

Application Notes: TAF11 antibody can be used for detection of TAF11 by ELISA at 1:312500. TAF11 antibody can be used for detection of TAF11 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TAF11 antibody at -20 °C.

Target Details for TAF11

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Alternative Name: TAF11 (TAF11 Products)

Synonyms: 1110038O14Rik antibody, 28kDa antibody, AI115401 antibody, AL024207 antibody, AW552398 antibody, PRO214 antibody, TAF2I antibody, TAFII28 antibody, MGC:15243 antibody, TATA-box binding protein associated factor 11 antibody, Taf11 antibody, TAF11 antibody

Background: TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.

Molecular Weight: 23 kDa

Gene ID: 6882

NCBI Accession: NP_005634

UniProt: Q15544