MLL4 antibody

Catalog No. ABIN2460789

Product Details anti-MLL4 Antibody

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL4 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MLL4.

Application Details

Application Notes: MLL4 antibody can be used for detection of MLL4 by ELISA at 1:12500. MLL4 antibody can be used for detection of MLL4 by western blot at 5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MLL4 antibody at -20 °C.

Target Details for MLL4

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Alternative Name: MLL4 (MLL4 Products)

Synonyms: HRX2 antibody, MLL1B antibody, MLL2 antibody, MLL4 antibody, TRX2 antibody, WBP7 antibody, 2610014H22Rik antibody, Mll2 antibody, Wbp7 antibody, mKIAA0304 antibody, ALR antibody, BC032281 antibody, BC058659 antibody, C430014K11Rik antibody, KMT2B antibody, Mll4 antibody, RGD1308331 antibody, lysine methyltransferase 2B antibody, lysine (K)-specific methyltransferase 2B antibody, lysine (K)-specific methyltransferase 2D antibody, KMT2B antibody, Kmt2b antibody, Kmt2d antibody

Background: MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer

Molecular Weight: 64 kDa, 294 kDa

Gene ID: 9757

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effect