AMFR antibody

Catalog No. ABIN2462647

Product Details anti-AMFR Antibody

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMFR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AMFR.

Application Details

Application Notes: AMFR antibody can be used for detection of AMFR by ELISA at 1:312500. AMFR antibody can be used for detection of AMFR by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store AMFR antibody at -20 °C.

Target Details for AMFR

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Alternative Name: AMFR (AMFR Products)

Synonyms: GP78 antibody, RNF45 antibody, gp78 antibody, wu:fi06e06 antibody, wu:fi37e05 antibody, zgc:63893 antibody, rnf45 antibody, autocrine motility factor receptor antibody, autocrine motility factor receptor L homeolog antibody, autocrine motility factor receptor a antibody, autocrine motility factor receptor, amfr antibody, putative autocrine motility factor receptor, amfr antibody, AMFR antibody, Amfr antibody, amfr.L antibody, amfra antibody, amfr antibody, AaeL_AAEL005881 antibody, CpipJ_CPIJ016043 antibody, Smp_047420 antibody

Background: Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. AMFR is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family (Gray et al., 2000).

Molecular Weight: 53 kDa, 53 kDa

Gene ID: 267

UniProt: Q6PGR1

Pathways: ER-Nucleus Signaling