CACNA1G antibody (AA 2052-2172) (Biotin)
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- Target See all CACNA1G Antibodies
- CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))
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Binding Specificity
- AA 2052-2172
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Reactivity
- Mouse
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CACNA1G antibody is conjugated to Biotin
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificity
- Detects ~<200 kDa. Does not cross-react with Cav3.2.
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Protein G Purified
- Immunogen
- Fusion protein amino acids 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1
- Clone
- S178A-9
- Isotype
- IgG1
- Top Product
- Discover our top product CACNA1G Primary Antibody
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- Application Notes
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Comment
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1 μg/ml of ABIN2483301 was sufficient for detection of Cav3.1 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Conjugated antibodies should be stored at 4°C
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- Target
- CACNA1G (Calcium Channel, Voltage-Dependent, T Type, alpha 1G Subunit (CACNA1G))
- Alternative Name
- Cav3.1 (CACNA1G Products)
- Synonyms
- CACNA1G antibody, cav3.1 antibody, ca(v)3.1 antibody, Ca(V)T.1 antibody, Cav3.1 antibody, NBR13 antibody, Cav3.1d antibody, [a]1G antibody, a1G antibody, alpha-1G antibody, mKIAA1123 antibody, Ca(v)3.1 antibody, calcium voltage-gated channel subunit alpha1 G antibody, calcium channel, voltage-dependent, T type, alpha 1G subunit antibody, calcium channel, voltage-dependent, T type, alpha 1G subunit L homeolog antibody, CACNA1G antibody, cacna1g antibody, cacna1g.L antibody, Cacna1g antibody
- Background
- Calcium channel CaV3.1 (a1G) is a low-voltage-activated T-type calcium channel. Such T-type channels are expressed throughout the body. In the heart, they may be involved in pacemaker current. In neurons, these channels may play a secondary pacemaker role (1). With the ubiquitous expression, it is not surprising that alterations in channel function have been implicated in disease. Drugs that act to block T-type calcium channels are used as anti-hypertensives, antiepileptic's, and blocking of T-type calcium channels may be involved in the action of some anesthetics and antipsychotics as well (1). Much remains to be determined about the precise cellular localization, in vivo physiological roles, roles in disease states and possible routes to modulate their structure/function to ameliorate effects of disease.
- Gene ID
- 12291
- NCBI Accession
- NP_001106284
- UniProt
- Q9WUT2
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