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IL7R antibody (PE-Cy5)

IL7R Reactivity: Human FACS Host: Mouse Monoclonal RDR5 PE-Cy5
Catalog No. ABIN2567211
  • Target See all IL7R Antibodies
    IL7R (Interleukin 7 Receptor (IL7R))
    Reactivity
    • 109
    • 49
    • 26
    • 7
    • 4
    • 2
    • 1
    Human
    Host
    • 81
    • 35
    • 27
    • 1
    • 1
    Mouse
    Clonality
    • 81
    • 62
    • 2
    Monoclonal
    Conjugate
    • 62
    • 11
    • 10
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL7R antibody is conjugated to PE-Cy5
    Application
    • 84
    • 77
    • 45
    • 26
    • 26
    • 13
    • 12
    • 9
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    RDR5
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product IL7R Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    IL7R (Interleukin 7 Receptor (IL7R))
    Alternative Name
    CD127 (IL7R Products)
    Synonyms
    IL7R antibody, CD127 antibody, IL-7Ralpha antibody, CDW127 antibody, IL-7R-alpha antibody, IL7RA antibody, ILRA antibody, IL-7RA antibody, interleukin 7 receptor antibody, IL7R antibody, Il7r antibody
    Background
    The RDR5 monoclonal antibody specifically reacts with human CD127, a 60-90 kDA type I transmembrane glycoprotein also known as the IL-7 receptor alpha chain. CD127 binds with CD132 (gamma c) to forms the IL-7 receptor that is expressed on mature T cells and immature B cells. Since CD127 expression is downregulated in Treg cells, it can be used as a marker for differentiating them from common T cells. The binding of the RDR5 antibody can be blocked by pre-incubating the cells with human IL-7.
    Gene ID
    3575
    UniProt
    P16871
    Pathways
    JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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