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CD40 Ligand antibody (FITC)

CD40LG Reactivity: Mouse FACS Host: Hamster Monoclonal MR1 FITC

Catalog No. ABIN2567255

Datasheet as PDF

Target See all CD40 Ligand (CD40LG) Antibodies

CD40 Ligand (CD40LG)
Reactivity
137

74

35

9

9

7

6

3

3

2

2

2

1

1

1

1
Mouse
Host
86

62

20

15

11

1
Hamster
Clonality
108

81

4
Monoclonal
Conjugate
101

22

20

14

9

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD40 Ligand antibody is conjugated to FITC
Application
105

100

54

48

37

31

20

16

14

14

13

13

7

4

4

4

3

3

2

2

2

1

1

1

1
Flow Cytometry (FACS)

Specificity

The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39.

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clone

MR1

Isotype

IgG

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CD40LG Reactivity: Human FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal CD40LG-2763 unconjugated

anti-CD40 Ligand (CD40LG) (AA 108-261) antibody
CD40LG Reactivity: Human FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal CD40LG-2761 unconjugated

anti-CD40 Ligand (CD40LG) antibody (FITC)
CD40LG Reactivity: Mouse FACS Host: Armenian Hamster Monoclonal MR-1 FITC

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CD40LG Reactivity: Human WB, FACS, IF, IHC (p) Host: Rabbit Polyclonal RB19150 unconjugated

anti-CD40 Ligand (CD40LG) (AA 79-129) antibody
CD40LG Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 33-62) antibody
CD40LG Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) (AA 111-261) antibody
CD40LG Reactivity: Pig WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD40 Ligand (CD40LG) antibody (PE)
CD40LG Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal 24-31 PE

anti-CD40 Ligand (CD40LG) (AA 47-261) antibody
CD40LG Reactivity: Human WB, FACS, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 8H10F5 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD40 Ligand (CD40LG)

Alternative Name

CD154 (CD40LG Products)

Synonyms

CD154 antibody, cd40l antibody, CD40L antibody, HIGM1 antibody, IGM antibody, IMD3 antibody, T-BAM antibody, TNFSF5 antibody, TRAP antibody, gp39 antibody, hCD40L antibody, CD40-L antibody, Cd40l antibody, Ly-62 antibody, Ly62 antibody, Tnfsf5 antibody, CD40 ligand antibody, TNF superfamily member 5 antibody, CD40LG antibody, cd40l antibody, Cd40lg antibody

Background

The MR1 monoclonal antibody specifically reacts with mouse CD154, a 39kDA transmembrane glycoprotein also known as CD40 ligand and gp39. CD154 is expressed on activated T cells and plays a role in B-T cell costimulation. The interaction of CD154 with CD40 induces B cell cycle entry and the signaling for T-dependent B cell activation. By interfering with this interaction, the MR1 antibody is reported to inhibit T and B lymphocyte activation.

Gene ID

21947

UniProt

P27548

Pathways

NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints