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PD-L1 antibody

PD-L1 Reactivity: Mouse FACS, Func Host: Rat Monoclonal 10F-9G2 unconjugated

Catalog No. ABIN2567407

Datasheet as PDF

Target See all PD-L1 Antibodies

PD-L1 (CD274 (PD-L1))
Reactivity
161

105

63

7

6

5

5

1

1
Mouse
Host
125

55

15

4

2

1
Rat
Compatible Secondaries
Clonality
108

92

2
Monoclonal
Conjugate
91

13

13

11

8

5

5

5

5

5

5

5

4

4

4

4

4

3

3

2

1

1

1
This PD-L1 antibody is un-conjugated
Application
135

99

56

40

37

28

16

16

14

14

10

7

5

4

3

3

2

1

1

1

1

1
Flow Cytometry (FACS), Functional Studies (Func)

Specificity

The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily.

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Clone

10F-9G2

Isotype

IgG2b kappa

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PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated

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PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6D9A2 unconjugated

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PD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (Extracellular Domain) antibody
PD-L1 Reactivity: Human IHC Host: Rabbit Monoclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC Host: Mouse Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Format

Liquid

Concentration

2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Storage

4 °C

Storage Comment

The product should be stored undiluted at 4°C. Do not freeze.
Target

PD-L1 (CD274 (PD-L1))

Alternative Name

CD274 (PD-L1 Products)

Synonyms

B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody

Background

The 10F.9G2 monoclonal antibody specifically reacts with mouse CD274, also known as B7-H1 or PD-L1, a 43 kDa glycoprotein of the B7 family of the immunoglobulin superfamily. CD274 is expressed on the B and T lymphocytes, natural killer cells, and dendritic cells. The receptor for the B7-H1 Molecule is PD-1, which contains an Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM), and is expressed on activated B and T cells. The interaction between CD274 and PD-1 seems to downregulate the T and B immune responses.

Gene ID

29126

UniProt

Q9NZQ7

Pathways

Cancer Immune Checkpoints