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Integrin beta 3 antibody

ITGB3 Reactivity: Human WB, FACS, IHC, Func Host: Mouse Monoclonal VI-PL2 unconjugated
Catalog No. ABIN2567868
  • Target See all Integrin beta 3 (ITGB3) Antibodies
    Integrin beta 3 (ITGB3)
    Reactivity
    • 170
    • 85
    • 49
    • 15
    • 14
    • 13
    • 12
    • 10
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 114
    • 59
    • 7
    • 2
    Mouse
    Clonality
    • 110
    • 70
    Monoclonal
    Conjugate
    • 92
    • 16
    • 12
    • 10
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 3 antibody is un-conjugated
    Application
    • 121
    • 75
    • 51
    • 48
    • 26
    • 24
    • 22
    • 18
    • 15
    • 13
    • 12
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Functional Studies (Func)
    Specificity
    The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography.
    Clone
    VI-PL2
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C. Do not freeze.
  • Target
    Integrin beta 3 (ITGB3)
    Alternative Name
    CD61 (ITGB3 Products)
    Synonyms
    BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody
    Background
    The VI-PL2 monoclonal antibody reacts with CD61, a type I integral transmembrane glycoprotein also known as integrin beta 3. CD61 forms a complex with CD41 (platelet gpIIb) and CD51 (integrin alphaV). It is expressed on osteoclasts, fibroblasts, platelets, macrophages, and megakaryocytes and appears to bind to fibronectin, vitronectin, thrombospondin, and fibrinogen and vWF. The VI-PL2 antibody is reported to be cross-reactive with baboon, rhesus, and cynomolgus.
    Gene ID
    3690
    UniProt
    P05106
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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