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CD8 alpha antibody (PerCP-Cy5.5)
CD8A
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
2-43
PerCP-Cy5.5
Product Details anti-CD8 alpha Antibody (PerCP-Cy5.5)
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Target
See all CD8 alpha (CD8A) Antibodies
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Reactivity
All reactivities for CD8 alpha antibodies
Mouse
Host
All hosts for CD8 alpha antibodies
Rat
Clonality
All clonalities for CD8 alpha antibodies
Monoclonal
Conjugate
All conjugates for CD8 alpha antibodies
This CD8 alpha antibody is conjugated to PerCP-Cy5.5
Application
All applications for CD8 alpha antibodies
Flow Cytometry (FACS)
Specificity
The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen.
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Clone
2-43
Isotype
IgG2b
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.2 mg/mL
Buffer
Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Storage
4 °C
Storage Comment
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target Details for CD8 alpha
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Target
CD8 alpha (CD8A)
(CD8a Molecule (CD8A))
Alternative Name
CD8a (CD8A Products )
Synonyms
cd8 antibody, LOC100136450 antibody, BB154331 antibody, Ly-2 antibody, Ly-35 antibody, Ly-B antibody, Lyt-2 antibody, zgc:136643 antibody, CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, RHACD8-4 antibody, CD8a molecule antibody, uncharacterized LOC100125537 antibody, CD8 alpha antibody, CD8 antigen, alpha chain antibody, T-cell surface glycoprotein CD8 alpha chain antibody, Cd8a antibody, LOC100125537 antibody, LOC100136450 antibody, CD8A antibody, cd8a antibody, LOC100126556 antibody
Background
The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells.
Gene ID
12525
UniProt
P01731
Pathways
TCR Signaling
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