IL-12/IL-23 p40 antibody
Reactivity: Mouse
FACS, ELISA, IF, IP, Func, WB
Host: Rat
Monoclonal
C17-8
unconjugated
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- Target See all IL-12/IL-23 p40 products
- IL-12/IL-23 p40
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This IL-12/IL-23 p40 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Functional Studies (Func), Western Blotting (WB)
- Specificity
- The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.
- Purification
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Clone
- C17-8
- Isotype
- IgG2a kappa
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anti-IL-12/IL-23 p40 antibody (APC)
Reactivity: Mouse FACS Host: Rat Monoclonal C17-8 APC
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Storage
- 4 °C
- Storage Comment
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- IL-12/IL-23 p40
- Abstract
- IL-12/IL-23 p40 Products
- Background
- The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.
- Gene ID
- 16160
- UniProt
- P43432
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