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IL-12/IL-23 p40 antibody (PE)

Reactivity: Mouse FACS Host: Rat Monoclonal C17-8 PE
Catalog No. ABIN2568233
  • Target See all IL-12/IL-23 p40 products
    IL-12/IL-23 p40
    Reactivity
    • 12
    • 3
    • 1
    Mouse
    Host
    • 12
    • 3
    Rat
    Clonality
    • 15
    Monoclonal
    Conjugate
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-12/IL-23 p40 antibody is conjugated to PE
    Application
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Specificity
    The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer.
    Purification
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Clone
    C17-8
    Isotype
    IgG2a kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Storage
    4 °C
    Storage Comment
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    IL-12/IL-23 p40
    Abstract
    IL-12/IL-23 p40 Products
    Background
    The C17.8 antibody specifically reacts with the p40 subunit of IL-12, as free monomer, as a homodimer, or as a part of the p70 dimer. C17.8 seems to neutralize the activity of mouse IL-12 and IL-23. IL-12 is the p70 heterodimer of p35 and p40, expressed by the macrophages, dendritic cells, and monocytes. The C17.8 antibody cross-reacts with IL-23, since IL-23 also contains one p40 subunit.
    Gene ID
    16160
    UniProt
    P43432
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