Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1/2 (GNAI1/GNAI2) antibody

Antigen: Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1/2 (GNAI1/GNAI2)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Cow (Bovine)

Application: Western Blotting (WB)

Catalog no.: ABIN265063

Additional Information

Characteristics: Synonyms: GNAI1, Guanine nucleotide-binding protein G(i) alpha-1 subunit

Alternative name: G protein alpha inhibitor 1 (+ GNAI2)

Gene ID: 2770

Swiss-Prot: P63096

Immunogen: Peptide corresponding to amino acids 345 - 354 of Gialpha1 and 346-355 of Gialpha2.

Cross-Reactivity: Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)

Isotype: IgG  (Matching secondary antibodies)

Description: GTP-binding proteins (G-proteins) play a critical role in signal transduction by couplingreceptors to effectors. The intracellular consequences of G-protein activation includesecond messenger generation, protein phosphorylation, ion channel activation, geneinduction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitiveG-proteins. Gi consists of three different subtypes of alpha-subunits (alphai1, aalphai2 andalphai3)

Specificity: This antibody reacts to Gi alpha 1/2. Species: Murine, Rat, Human, Bovine. Others not tested.

Application Details

Application Notes: Western Blot: 5 - 10 ug/ml. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: Lot specific

Purification: Purified

Buffer: Phosphate buffered saline with 0.08% sodium azide

Storage: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch.

Restrictions: For Research Use only