GNAI1 antibody (AA 345-354)

Catalog No. ABIN265063

This Rabbit Polyclonal antibody specifically detects GNAI1 in WB. It exhibits reactivity toward Human, Mouse, Rat and Cow.

Quick Overview for GNAI1 antibody (AA 345-354) (ABIN265063)

Target: GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNAI1 Antibody

Binding Specificity: AA 345-354

Specificity: This antibody reacts to Gi alpha 1/2.

Cross-Reactivity (Details): Also reacts to: GNAI2

Purification: Purified

Immunogen: Peptide corresponding to amino acids 345 - 354 of Gialpha1 and 346-355 of Gialpha2.

Isotype: IgG

Application Details

Application Notes: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Target Details for GNAI1

Target: GNAI1 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1))

Background: GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of alpha-subunits (alphai1, aalphai2 and alphai3)Synonyms: GNAI1, Guanine nucleotide-binding protein G(i) alpha-1 subunit

Gene ID: 2770

NCBI Accession: NP_002060

UniProt: P63096

Pathways: G-protein mediated Events