SGPP1 antibody

Catalog No. ABIN4620339

The Rabbit Polyclonal anti-SGPP1 antibody is suitable to detect SGPP1 in samples from Human. It has been validated for WB.

Quick Overview for SGPP1 antibody (ABIN4620339)

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGPP1 Antibody

Specificity: This antibody reacts to Sphingosine 1-Phosphate Phosphatase 1.

Purification: Affinity Purified

Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate phosphatase 1 protein.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1: 200, Tissue lysate should be used at 10-50 g/lane. Positive Control: Human brain lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped on dry ice. Store (in aliquots) at -20 °C only.

Target Details for SGPP1

Target: SGPP1 (Sphingosine-1-Phosphate Phosphatase 1 (SGPP1))

Alternative Name: SGPP1

Background: Sphingosine 1-phosphate (S1P) is a highly bioactive lipid that has a myriad of biological effects both intracellularly as a second messenger and extracellularly by binding to the S1P(1-5)/G-protein-coupled receptors of the endothelial differentiation gene family. Intracellularly, at least two enzymes, sphingosine kinase (1 and 2) and S1P phosphatase, regulate the activity of S1P by governing the phosphorylation of S1P. Regulation of hS1Pase1 with the resultant changes in cellular and secreted S1P has important implications in cell proliferation, angiogenesis and apoptosis.Synonyms: SPPase1, Sphingosine-1-phosphatase 1, Sphingosine-1-phosphate phosphatase 1

Gene ID: 81537

NCBI Accession: NP_110418

UniProt: Q9BX95