Cadherin 1 (CDH1) antibody

Antigen: Cadherin 1 (CDH1)

Synonyms: cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Catalog no.: ABIN265391

Additional Information

Characteristics: Synonyms: Epithelial cadherin, E-cadherin, Uvomorulin, CAM 120/80, CDH1, CDHE, UVO

Alternative name: CD324 / Cadherin-1

Swiss-Prot: P12830

Cross-Reactivity: Human

Description: Cadherins comprise a family of Ca+-dependent adhesion molecules that function tomediate cell-cell binding critical to the maintenance of tissue structure andmorphogenesis. The classical cadherins, E-, N- and P-cadherin, consist of largeextracellular domains characterized by a series of five homologous NH2 terminal repeats. The most distal of these cadherins is thought to be responsible for binding specificity,transmembrane domains and carboxyterminal intracellular domains. The relatively shortintracellular domains interact with a variety of cytoplasmic proteins, such as beta-Catenin,to regulate cadherin function. Members of this family of adhesion proteins include ratcadherin K (and its human homolog, cadherin-6), R-cadherin, B-cadherin, E/P- cadherinand cadherin-5.

Specificity: This antibody detects endogenous levels of E-Cadherin protein. Species: Human. Others not tested.

Synonyms: cdh1, E-cadherin, si:dz180o5.2, dZ71B9.1, si:dz180o5.1, CDH1, uvo, lcam, E-Cad, XBcad, l-cam, xcdh1, cdhc-A, xb-cad, XTCAD-1, c-cadherin, cadherin-1, uvomorulin, XB-cadherin, UVO, CDHE, ECAD, LCAM, Arc-1, CD324, HPT1, CDH16, HPT-1, FLJ26931, MGC138218, MGC142024, cad17, hpt1, cdh16, hpt-1, LI-cadherin, cadherin-17

Application Details

Application Notes: ELISA: 1/40000~1/60000. Western Blot: 1/500~1/1000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50-1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Concentration: 1.0 mg/ml

Purification: Aff - Purified

Buffer: Phosphate buffered saline (PBS), pH~7.2 containing 15 mM Sodium Azideas preservative.

Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: One year from despatch.

Research Area: Extracellular Matrix, Signaling, Cytoskeleton

Restrictions: For Research Use only