Galectin 3 antibody

Catalog No. ABIN265430

Product Details anti-Galectin 3 Antibody

Target: Galectin 3 (LGALS3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Galectin 3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: ELISA: 1/1000approx. 1/10000. Western Blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50approx. 1/200. Immunofluorescence: 1/50approx. 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Galectin 3

Target: Galectin 3 (LGALS3)

Alternative Name: Galectin-3 (LGALS3 Products)

Synonyms: CBP 35 antibody, Gal-3 antibody, Galectin-3 antibody, leg3 antibody, galactoside-binding antibody, galectin-3 antibody, lectin antibody, soluble antibody, CBP35 antibody, GAL3 antibody, GALBP antibody, GALIG antibody, L31 antibody, LGALS2 antibody, MAC2 antibody, MGC52947 antibody, MGC75803 antibody, LGALS3 antibody, gal-3 antibody, GBP antibody, L-34 antibody, Mac-2 antibody, gal3 antibody, galectin 3 antibody, Galectin-3 antibody, avian beta-defensin 3 antibody, lectin, galactoside-binding, soluble, 3 L homeolog antibody, lectin, galactoside-binding, soluble, 3 antibody, galectin 2 antibody, lectin, galactose binding, soluble 3 antibody, LGALS3 antibody, leg3 antibody, AvBD3 antibody, lgals3.L antibody, lgals3 antibody, LGALS2 antibody, Lgals3 antibody

Target Type: Chemical

Background: The galectin-3 protein, also known as Mac-2, hMac-2, GALBP, CBP35 or LGALS3, contains a single carbohydrate binding domain, which binds galactose-containing glycoconjugates. galectin-3 is expressed in colonic and intestinal epithelium, inflammatory macrophages, papillary and follicular carcinomas, neoplastic astrocytes and some B and T lymphocytes. Upregulated expression of galectin-3 is involved in cancer progression and metastasis. galectin-3 mediates the endocytosis of β-1 Integrins in a lactose-dependant manner and is associated with thyroid malignancy and Crohn's disease. It may also be used as a marker for diagnosing cases involving Hurthle cell adenomas and carcinomas.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2

Molecular Weight: approx. 30 kDa

Gene ID: 9606

UniProt: P17931

Pathways: RTK Signaling