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P-Selectin antibody (Alexa Fluor 488)
SELP
Reactivity: Human
FACS
Host: Mouse
Monoclonal
AK4
Alexa Fluor 488
Product Details anti-P-Selectin Antibody (Alexa Fluor 488)
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Target
See all P-Selectin (SELP) Antibodies
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Reactivity
All reactivities for P-Selectin antibodies
Human
Host
All hosts for P-Selectin antibodies
Mouse
Clonality
All clonalities for P-Selectin antibodies
Monoclonal
Conjugate
All conjugates for P-Selectin antibodies
This P-Selectin antibody is conjugated to Alexa Fluor 488
Application
All applications for P-Selectin antibodies
Flow Cytometry (FACS)
Cross-Reactivity
Chimpanzee
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.
Clone
AK4
Isotype
IgG1 kappa
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Alternatives
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP
Reactivity: Human, Mouse, Rat, Pig
WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for P-Selectin
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Target
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Alternative Name
CD62P (SELP Products )
Synonyms
PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody
Background
CD62P is a 140 kD type I transmembrane glycoprotein also known as P-selectin, platelet activation-dependent granule membrane protein (PADGEM), and GMP-140. It is expressed on activated platelets, megakaryocytes, and endothelial cells. CD62 is primarily stored in secretory α-granules in platelets and Weibel-Palade bodies in endothelial cells, and is rapidly relocated to the plasma membrane upon activation. The ligands for CD62P are CD162 and CD24. A primary function of CD62P is cell adhesion during neutrophil rolling, and platelet-neutrophil and platelet-monocyte interactions.
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