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P-Selectin antibody
SELP
Reactivity: Human, Rat
IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-P-Selectin Antibody
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Target
See all P-Selectin (SELP) Antibodies
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Reactivity
All reactivities for P-Selectin antibodies
Human, Rat
Host
All hosts for P-Selectin antibodies
Rabbit
Clonality
All clonalities for P-Selectin antibodies
Polyclonal
Conjugate
All conjugates for P-Selectin antibodies
This P-Selectin antibody is un-conjugated
Application
All applications for P-Selectin antibodies
Immunohistochemistry (IHC)
Characteristics
Polyclonal Antibody
Purification
Affinity purification
Immunogen
Recombinant fusion protein of human SELP (NP_002996.2).
Isotype
IgG
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Alternatives
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anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) (AA 701-768) antibody
SELP
Reactivity: Human, Mouse, Rat, Pig
WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
IHC 1:50-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for P-Selectin
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Target
P-Selectin (SELP)
(Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
Alternative Name
SELP (SELP Products )
Synonyms
PSELECT antibody, CD62 antibody, CD62P antibody, GMP140 antibody, GRMP antibody, LECAM3 antibody, PADGEM antibody, PSEL antibody, GMP-140 antibody, Grmp antibody, selectin P antibody, selectin, platelet antibody, Selp antibody, SELP antibody
Background
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.
Gene ID
6403
UniProt
P16109
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