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CD11c antibody (Alexa Fluor 647)
ITGAX
Reactivity: Mouse
FACS
Host: Hamster
Monoclonal
N418
Alexa Fluor 647
Product Details anti-CD11c Antibody (Alexa Fluor 647)
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Target
See all CD11c (ITGAX) Antibodies
CD11c (ITGAX)
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Reactivity
All reactivities for CD11c antibodies
Mouse
Host
All hosts for CD11c antibodies
Hamster
Clonality
All clonalities for CD11c antibodies
Monoclonal
Conjugate
All conjugates for CD11c antibodies
This CD11c antibody is conjugated to Alexa Fluor 647
Application
All applications for CD11c antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
Clone
N418
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C
Target Details for CD11c
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Target
CD11c (ITGAX)
(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))
Alternative Name
CD11c (ITGAX Products )
Synonyms
CD11C antibody, SLEB6 antibody, RGD1561123 antibody, AI449405 antibody, Cd11c antibody, Cr4 antibody, N418 antibody, integrin subunit alpha X antibody, integrin alpha X antibody, ITGAX antibody, Itgax antibody
Background
CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.
Pathways
Complement System , Activated T Cell Proliferation , Integrin Complex
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