CCR6 antibody (APC)

Catalog No. ABIN2658519

Product Details anti-CCR6 Antibody (APC)

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This CCR6 antibody is conjugated to APC

Application: Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)

Purification: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Clone: 29-2L17

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from prolonged exposure to light. Do not freeze.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Alternative Name: CD196 (CCR6 Products)

Synonyms: BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody

Background: CCR6 is a G-protein linked chemokine receptor which binds the chemokine CCL20/MIP-3a. It is expressed on B lymphocytes and certain subsets of dendritic cells and T cells. CCR6 is reported to be involved in mucosal immune response and lymphocyte migration and homeostasis.

Pathways: cAMP Metabolic Process