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CD103 antibody (FITC)
ITGAE
Reactivity: Rat
ICFC
Host: Mouse
Monoclonal
OX-62
FITC
Product Details anti-CD103 Antibody (FITC)
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Target
See all CD103 (ITGAE) Antibodies
CD103 (ITGAE)
(Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
Reactivity
All reactivities for CD103 antibodies
Rat
Host
All hosts for CD103 antibodies
Mouse
Clonality
All clonalities for CD103 antibodies
Monoclonal
Conjugate
All conjugates for CD103 antibodies
This CD103 antibody is conjugated to FITC
Application
All applications for CD103 antibodies
Intracellular Flow Cytometry (ICFC)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
OX-62
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for CD103
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Target
CD103 (ITGAE)
(Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
Alternative Name
CD103 (ITGAE Products )
Synonyms
A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody
Background
CD103, also known as Integrin αE or integrin αIEL, is a single pass transmembrane protein composed by two chains, heavy and light, linked by a disulfide bond. It is expressed in the cell surface as an αE/β7 heterodimer. CD103 mediates adhesion of intraepithelial T cells (IEL) to the epithelium. CD103 is expressed by IEL, effector and memory Tregs, and dendritic cells and their immediate precursors. E-cadherin is the ligand for CD103.
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