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VCAM1 antibody (FITC)
VCAM1
Reactivity: Mouse
FACS
Host: Rat
Monoclonal
429 (MVCAM-A)
FITC
Product Details anti-VCAM1 Antibody (FITC)
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Target
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VCAM1
(Vascular Cell Adhesion Molecule 1 (VCAM1))
Reactivity
All reactivities for VCAM1 antibodies
Mouse
Host
All hosts for VCAM1 antibodies
Rat
Clonality
All clonalities for VCAM1 antibodies
Monoclonal
Conjugate
All conjugates for VCAM1 antibodies
This VCAM1 antibody is conjugated to FITC
Application
All applications for VCAM1 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
429 (MVCAM-A)
Isotype
IgG2a kappa
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for VCAM1
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Target
VCAM1
(Vascular Cell Adhesion Molecule 1 (VCAM1))
Alternative Name
CD106 (VCAM1 Products )
Synonyms
CD106 antibody, INCAM-100 antibody, Vcam-1 antibody, VCAM1B antibody, fi76d06 antibody, wu:fi76d06 antibody, zgc:158875 antibody, VCAM1 antibody, vascular cell adhesion molecule 1 antibody, vascular cell adhesion molecule 1b antibody, VCAM1 antibody, Vcam1 antibody, vcam1b antibody, VCAM-1 antibody
Background
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.
Pathways
Carbohydrate Homeostasis
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