×
For best experience we recommend to activate Javascript in your browser.
SIRPA antibody (FITC)
SIRPA
Reactivity: Mouse
IHC, ELISA, ICFC, CyTOF
Host: Rat
Monoclonal
P84
FITC
Product Details anti-SIRPA Antibody (FITC)
(hide)
Target
See all SIRPA Antibodies
SIRPA
(Signal-Regulatory Protein alpha (SIRPA))
Reactivity
All reactivities for SIRPA antibodies
Mouse
Host
All hosts for SIRPA antibodies
Rat
Clonality
All clonalities for SIRPA antibodies
Monoclonal
Conjugate
All conjugates for SIRPA antibodies
This SIRPA antibody is conjugated to FITC
Application
All applications for SIRPA antibodies
Immunohistochemistry (IHC), ELISA, Intracellular Flow Cytometry (ICFC), Mass Cytometry (CyTOF)
Purification
The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Clone
P84
Isotype
IgG1 kappa
Top Product
Discover our top product SIRPA Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Protect from prolonged exposure to light. Do not freeze.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for SIRPA
(hide)
Target
SIRPA
(Signal-Regulatory Protein alpha (SIRPA))
Alternative Name
CD172a (SIRPA Products )
Synonyms
BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody
Background
CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.
Recently viewed
(hide)