Flow Cytometry (FACS), Cytometry by Time of Flight (CyTOF)
Purification
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
CLEC4D antibody, CLEC-6 antibody, CLEC6 antibody, CLECSF8 antibody, MCL antibody, MPCL antibody, Clecsf8 antibody, Mpcl antibody, mcl antibody, Mcl antibody, C-type lectin domain family 4 member D antibody, C-type lectin domain family 4, member d antibody, C-type lectin domain family 4, member D antibody, CLEC4D antibody, LOC611536 antibody, Clec4d antibody
Background
CD368 (CLEC4D), also known as CLEC6, is a 30 kD single pass type II transmembrane protein and member of the C-type lectin-like domain (CTLD) superfamily. CLEC4D is an endocytic receptor, probably involved in antigen presentation, cell adhesion, and cell signaling. CLEC4D is expressed by macrophages, monocytes, neutrophils, and a subset of dendritic cells and is upregulated by IL-6, IL-10, TNF-α, and IFN-γ.