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CCR7 antibody (PE)

CCR7 Reactivity: Mouse FACS Host: Rat Monoclonal 4B12 PE
Catalog No. ABIN2663130
  • Target See all CCR7 Antibodies
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Reactivity
    • 84
    • 48
    • 37
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    Mouse
    Host
    • 66
    • 18
    • 7
    • 4
    Rat
    Clonality
    • 60
    • 34
    • 1
    Monoclonal
    Conjugate
    • 44
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CCR7 antibody is conjugated to PE
    Application
    • 51
    • 48
    • 21
    • 19
    • 15
    • 15
    • 14
    • 14
    • 13
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    4B12
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CCR7 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
    Alternative Name
    CD197 (CCR7 Products)
    Synonyms
    zgc:165629 antibody, ccr7-a antibody, CD197 antibody, Cdw197 antibody, Cmkbr7 antibody, EBI1 antibody, Ebi1h antibody, BLR2 antibody, CDw197 antibody, CMKBR7 antibody, chemokine (C-C motif) receptor 7 antibody, C-C motif chemokine receptor 7 antibody, C-C motif chemokine receptor 7 L homeolog antibody, ccr7 antibody, CCR7 antibody, ccr7.L antibody, Ccr7 antibody
    Background
    CD197 is also known as C-C chemokine receptor 7 (CCR7) or EBI-1. CCR7 is a G-coupled rhodopsin-like member of the GPCR superfamily with a predicted molecular weight of 43 kD that is expressed on hematopoietic stem cells, most naive T cells, some memory T cells, B subset, and mature dendritic cells. CCR7 is a receptor for the chemokines CCL19 (MIP3 beta) and SLC (6CKine, Exodus-2, TCA-4, CCL21) that plays a role in thymocytes development, T cell adhesion at intestinal sites, the homeostatic recirculation of memory T cells, and chemotaxis.
    Pathways
    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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