DcR1 (TNFRSF10C)
(Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
Reactivity
Mouse
Host
Armenian Hamster
Clonality
Monoclonal
Conjugate
This DcR1 antibody is conjugated to PE
Application
Western Blotting (WB)
Purification
The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Mouse Decoy Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Receptor 1 (mDcTRAIL R1) is a GPI-anchored mouse TNF receptor super-family member that lacks a cytoplasmic death domain. It expresses on many cell types, including some tumor cells. mDcTRAIL R1 appears to have a negative effect against TRAIL receptors because it lacks an intracellular death domain, and produces a competitive blockage of TRAIL-mediated apoptosis. The role of the DcR1 in apoptosis has not yet been clarified.