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DcR1 antibody (PE)

TNFRSF10C Reactivity: Mouse WB Host: Armenian Hamster Monoclonal mDcR1-3 PE
Catalog No. ABIN2663675
  • Target See all DcR1 (TNFRSF10C) Antibodies
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Reactivity
    • 55
    • 7
    • 7
    • 6
    Mouse
    Host
    • 41
    • 19
    • 1
    • 1
    Armenian Hamster
    Clonality
    • 43
    • 19
    Monoclonal
    Conjugate
    • 30
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DcR1 antibody is conjugated to PE
    Application
    • 38
    • 23
    • 21
    • 13
    • 13
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    MDcR1-3
    Isotype
    IgG
    Top Product
    Discover our top product TNFRSF10C Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
    Alternative Name
    DcTRAIL-R1 (TNFRSF10C Products)
    Synonyms
    CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
    Background
    Mouse Decoy Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Receptor 1 (mDcTRAIL R1) is a GPI-anchored mouse TNF receptor super-family member that lacks a cytoplasmic death domain. It expresses on many cell types, including some tumor cells. mDcTRAIL R1 appears to have a negative effect against TRAIL receptors because it lacks an intracellular death domain, and produces a competitive blockage of TRAIL-mediated apoptosis. The role of the DcR1 in apoptosis has not yet been clarified.
    Pathways
    Apoptosis
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