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SEMA4D/CD100 antibody
SEMA4D
Reactivity: Mouse
FACS, IF
Host: Rat
Monoclonal
BMA-12
unconjugated
Product Details anti-SEMA4D/CD100 Antibody
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Target
See all SEMA4D/CD100 (SEMA4D) Antibodies
SEMA4D/CD100 (SEMA4D)
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Reactivity
All reactivities for SEMA4D/CD100 antibodies
Mouse
Host
All hosts for SEMA4D/CD100 antibodies
Rat
Clonality
All clonalities for SEMA4D/CD100 antibodies
Monoclonal
Conjugate
All conjugates for SEMA4D/CD100 antibodies
This SEMA4D/CD100 antibody is un-conjugated
Application
All applications for SEMA4D/CD100 antibodies
Flow Cytometry (FACS), Immunofluorescence (IF)
Purification
The antibody was purified by affinity chromatography.
Clone
BMA-12
Isotype
IgG2a kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for SEMA4D/CD100
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Target
SEMA4D/CD100 (SEMA4D)
(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))
Alternative Name
CD100 (SEMA4D Products )
Synonyms
C9orf164 antibody, CD100 antibody, M-sema-G antibody, SEMAJ antibody, coll-4 antibody, Semacl2 antibody, Semaj antibody, Semcl2 antibody, COLL-4 antibody, semaphorin 4D antibody, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D antibody, Sema4d antibody, SEMA4D antibody
Background
CD100, also known as Semaphorin-4D (SEMA4D), is a 150 kD, type I transmembrane protein, with one sema domain and one C2-type Ig domain. It is found as a homodimer on the cell surface. CD100 is expressed in the brain, kidney, heart, the majority of hematopoietic cells, and some malignant cells. CD100 is a potent inducer of angiogenesis and inhibitor of bone formation, and plays a role in lymphocyte activation, antibody production, dendritic cell maturation, and axon guidance. Its ligands are CD72 and Plexin-B1. CD100 is cleaved from the membrane of activated T and B cells, producing a soluble form.
Pathways
Regulation of Cell Size
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