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LAMP1 antibody
LAMP1
Reactivity: Human
FACS, IHC, IF
Host: Mouse
Monoclonal
H4A3
unconjugated
Product Details anti-LAMP1 Antibody
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Target
See all LAMP1 Antibodies
LAMP1
(Lysosomal-Associated Membrane Protein 1 (LAMP1))
Reactivity
All reactivities for LAMP1 antibodies
Human
Host
All hosts for LAMP1 antibodies
Mouse
Clonality
All clonalities for LAMP1 antibodies
Monoclonal
Conjugate
All conjugates for LAMP1 antibodies
This LAMP1 antibody is un-conjugated
Application
All applications for LAMP1 antibodies
Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
Cross-Reactivity
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Baboon, Chimpanzee, Pigtailed Macaque, Rhesus Monkey, Green Monkey (Chlorocebus sabaeus)
Purification
The antibody was purified by affinity chromatography.
Clone
H4A3
Isotype
IgG1 kappa
Top Product
Discover our top product LAMP1 Primary Antibody
Alternatives
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anti-Lysosomal-Associated Membrane Protein 1 (LAMP1) (AA 301-417) antibody
LAMP1
Reactivity: Human, Mouse, Rat, Monkey
WB, FACS, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for LAMP1
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Target
LAMP1
(Lysosomal-Associated Membrane Protein 1 (LAMP1))
Alternative Name
CD107a (LAMP1 Products )
Synonyms
CD107a antibody, LAMPA antibody, LGP120 antibody, AI196048 antibody, Lamp-1 antibody, LEP100 antibody, LAMP-1 antibody, LGP-A antibody, Lgpa antibody, Lysosome-associated membrane protein 1 antibody, cd107a antibody, lamp-1 antibody, lamp1 antibody, lampa antibody, lgp120 antibody, rexp76 antibody, lysosomal associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 antibody, lysosomal-associated membrane protein 1 L homeolog antibody, LAMP1 antibody, Lamp1 antibody, lamp1.L antibody
Background
CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.
Pathways
Autophagy
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