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PVRL2 antibody
PVRL2
Reactivity: Human
FACS
Host: Mouse
Monoclonal
TX31
unconjugated
Product Details anti-PVRL2 Antibody
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Target
See all PVRL2 Antibodies
PVRL2
(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
Reactivity
All reactivities for PVRL2 antibodies
Human
Host
All hosts for PVRL2 antibodies
Mouse
Clonality
All clonalities for PVRL2 antibodies
Monoclonal
Conjugate
All conjugates for PVRL2 antibodies
This PVRL2 antibody is un-conjugated
Application
All applications for PVRL2 antibodies
Flow Cytometry (FACS)
Purification
The antibody was purified by affinity chromatography.
Clone
TX31
Isotype
IgG1 kappa
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Discover our top product PVRL2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for PVRL2
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Target
PVRL2
(Poliovirus Receptor-Related 2 (Herpesvirus Entry Mediator B) (PVRL2))
Alternative Name
CD112 (PVRL2 Products )
Synonyms
prr2 antibody, AI325026 antibody, AI987993 antibody, Cd112 antibody, MPH antibody, Pvr antibody, Pvs antibody, nectin-2 antibody, CD112 antibody, HVEB antibody, PRR2 antibody, PVRR2 antibody, nectin cell adhesion molecule 2 antibody, Nectin2 antibody, NECTIN2 antibody
Background
CD112, known as poliovirus receptor related 2 protein (PRR2), Nectin-2, or Hve B, is a type I transmembrane glycoprotein, a member of the Ig gene superfamily. It is primarily found on myelomonocytic cells, megakaryocytes, dendritic cells, mast cells, CD34 positive stem cells, endothelial cells, epithelial cells, and neuronal cells. CD112 functions as a receptor for α-herpes viruses HSV-1 and pseudorabies virus (PRV). CD112 is an adhesion molecule involved in the formation of cell junction and regulation of NK- and T cell-mediated cytotoxicity through interaction with CD226 (DNAM-1) and other nectin family molecules.
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Cell-Cell Junction Organization
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