TNFRSF18 antibody
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- Target See all TNFRSF18 Antibodies
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TNFRSF18 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Intracellular Flow Cytometry (ICFC)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- 621
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TNFRSF18 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) antibody
TNFRSF18 Reactivity: Human FACS, ELISA, WB, IHC, ICC, Neut Host: Mouse Monoclonal 2A7A6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 266-162) antibodyTNFRSF18 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM78 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 201-274) antibodyTNFRSF18 Reactivity: Human ELISA, IF (p), IF (cc), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 184-241) antibodyTNFRSF18 Reactivity: Human FACS, ELISA, WB, IHC, ICC, Neut Host: Mouse Monoclonal 6H8B9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 90-162) antibodyTNFRSF18 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 1-241) antibodyTNFRSF18 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) antibodyTNFRSF18 Reactivity: Human ELISA, WB Host: Mouse Monoclonal 2H4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (C-Term) antibodyTNFRSF18 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) antibodyTNFRSF18 Reactivity: Human, Mouse ELISA, WB, IHC, IHC (p) Host: Mouse Monoclonal 2H4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 50-177) antibodyTNFRSF18 Reactivity: Human FACS, ELISA Host: Rabbit Monoclonal DM52 unconjugated Recombinant Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- Alternative Name
- CD357 (TNFRSF18 Products)
- Synonyms
- GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
- Background
- GITR (glucocorticoid-induced TNF receptor family-regulated gene) is a 25 kD TNF receptor superfamily member (also known as AITR and TNFRSF18). GITR is expressed on activated lymphocytes and is upregulated by T cell receptor engagement. The cytoplasmic domain of GITR is homologous to CD40, 4-1BB and CD27 and has been shown to interact with TRAF 1-3, but not TRAF 5 or 6. GITR signaling has been shown to regulate T cell proliferation and TCR-mediated apoptosis, and to break immunological self-tolerance. GITR binds GITRL and is involved in the development of regulatory T cells and to regulate the activity of Th1 subsets.
- Pathways
- Cancer Immune Checkpoints
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